Semax 10mg

With FREE BAC Water

COAs available upon request

Semax Peptide

Overview

Semax is a laboratory-produced peptide developed from the ACTH (adrenocorticotropic hormone) 4–10 sequence and was first created by researchers in Russia. Unlike the original hormone, Semax does not exhibit corticosteroid activity, making it an attractive candidate for investigating neurological function without the hormonal effects associated with ACTH.

Preclinical and laboratory research has focused on Semax for its potential involvement in cognitive performance, neuroprotection, and the body's adaptive response to stress. Although it is not approved for therapeutic use in most countries, Semax continues to be extensively studied in neuroscience and peptide research.

Research Applications

Semax has been investigated across a number of experimental research areas, including:

Neuroprotection
Laboratory studies have explored Semax for its potential to support neuronal survival and reduce oxidative damage in models of cerebral ischemia and traumatic brain injury.

Cognitive Function
Researchers have examined its possible nootropic properties, including effects on memory formation, learning processes, concentration, and attention.

Mood and Neurotransmitter Activity
Preclinical investigations suggest that Semax may influence neurotransmitter systems, particularly those involving dopamine and serotonin, making it an area of interest in behavioural and neurological research.

Neurotrophic Signalling
Studies have also evaluated Semax for its potential effects on the expression of brain-derived neurotrophic factor (BDNF) and other proteins involved in neuronal growth, plasticity, and repair.

Collectively, these areas of investigation have established Semax as an important research peptide for studying cognitive function, neurological resilience, and mechanisms involved in brain health and recovery.

Technical Specifications

• Chemical Name: Met-Glu-His-Phe-Pro-Gly-Pro
• Alternative Names: Semax; ACTH(4–7)-Pro-Gly-Pro
• Molecular Formula: C₃₇H₅₁N₉O₁₀S
• Molecular Weight: Approximately 751.9 g/mol
• Amino Acid Sequence: MEHFPGP
• CAS Number: 80714-61-0
• Peptide Classification: Synthetic heptapeptide derived from the ACTH (4–10) fragment

Storage Recommendations

• Lyophilized Semax is stable at room temperature for short-term handling.
• For long-term preservation, store at −20 °C or colder.
• Following reconstitution, refrigerate at 2 °C to 8 °C. Stability after mixing may vary depending on the solvent and storage conditions.

Solubility

Semax readily dissolves in sterile water and compatible aqueous buffer solutions, with solubility influenced by the peptide's purity and formulation.

References

Alekseeva, E. V., Andreeva, L. A., Kamensky, A. A., et al. (1992). Neuropeptide Semax: behavioral effects and mechanism of action. Neuroscience and Behavioral Physiology, 22(6), 475–479.

Myasoedov, N. F., Kamensky, A. A., & Ashmarin, I. P. (1997). Peptide Semax in the prevention and treatment of experimental cerebral ischemia. Pathophysiology, 4(4), 273–277.

Inozemtsev, A. N., Kamensky, A. A., & Ashmarin, I. P. (2008). Semax and neurotrophin expression: insights into peptide modulation of the nervous system. Doklady Biological Sciences, 418(1), 17–19.

Research compound only. Not for human consumption