{"product_id":"motsc-10mg","title":"MOTsC 10mg","description":"\u003ch3\u003eWith \u003cstrong\u003e\u003cem\u003eFREE\u003c\/em\u003e\u003c\/strong\u003e BAC Water\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eCOAs available upon request\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003e\u003cspan\u003eMOTS-c Peptide\u003c\/span\u003e\u003c\/h2\u003e\n\u003ch3\u003e\u003cspan\u003eOverview\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp class=\"isSelectedEnd\"\u003e\u003cspan\u003eMOTS-c is a mitochondrial-derived peptide encoded by mitochondrial DNA, making it distinct from most peptides used in biomedical research. Since its discovery, it has become an important subject of preclinical investigation due to its potential involvement in regulating cellular metabolism, energy balance, and adaptive stress responses. Although MOTS-c is not approved for therapeutic use, it continues to attract significant interest in laboratory and academic research focused on metabolism, exercise physiology, and healthy aging.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eResearch Applications\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp class=\"isSelectedEnd\"\u003e\u003cspan\u003eCurrent scientific research has explored MOTS-c across several key areas of interest:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"isSelectedEnd\"\u003e\u003cstrong\u003e\u003cspan\u003eMetabolic Regulation\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan\u003eExperimental studies have investigated MOTS-c for its potential role in glucose utilisation, lipid metabolism, and the maintenance of metabolic homeostasis.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"isSelectedEnd\"\u003e\u003cstrong\u003e\u003cspan\u003eExercise Physiology\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan\u003ePreclinical findings suggest that MOTS-c may influence biological pathways associated with exercise adaptation, making it an area of interest in studies of endurance, skeletal muscle function, and physical performance.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"isSelectedEnd\"\u003e\u003cstrong\u003e\u003cspan\u003eHealthy Aging Research\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan\u003eResearchers are examining the peptide's involvement in cellular resilience and molecular pathways linked to longevity and age-related metabolic health.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"isSelectedEnd\"\u003e\u003cstrong\u003e\u003cspan\u003eCellular Stress Response\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan\u003eMOTS-c has also been evaluated for its potential role in helping cells respond to oxidative stress and metabolic challenges, with ongoing studies investigating its contribution to cellular protection mechanisms.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"isSelectedEnd\"\u003e\u003cspan\u003eThese areas of investigation have positioned MOTS-c as a promising research molecule within the field of mitochondrial biology, particularly in studies involving energy metabolism, cellular adaptation, and the biology of aging.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eTechnical Specifications\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul data-spread=\"false\"\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan\u003eChemical Name:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Mitochondrial-Derived Peptide MOTS-c\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan\u003eAlternative Names:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e MOTSc; Mitochondrial Open Reading Frame of the 12S rRNA Type-c\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan\u003eMolecular Formula:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e C₃₇₇H₆₄₀N₁₀₆O₁₂₆S\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan\u003eMolecular Weight:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Approximately 2171 g\/mol\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan\u003eAmino Acid Sequence:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan\u003eCAS Number:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e 1465911-04-7\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan\u003ePeptide Classification:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Mitochondrial-Derived Peptide (MDP)\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cspan\u003eStorage Recommendations\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul data-spread=\"false\"\u003e\n\u003cli\u003e\u003cspan\u003eLyophilized MOTS-c is stable at room temperature for short-term handling.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eFor long-term preservation, store at \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003e−20 °C or below\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eAfter reconstitution, refrigerate between \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003e2 °C and 8 °C\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e. Stability following reconstitution will depend on the solvent and storage conditions.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cspan\u003eSolubility\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp class=\"isSelectedEnd\"\u003e\u003cspan\u003eMOTS-c is generally soluble in sterile water and compatible aqueous buffer solutions, with solubility varying according to formulation and purity.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eReferences\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp class=\"isSelectedEnd\"\u003e\u003cspan\u003eLee, C., Zeng, J., Drew, B. G., et al. (2015). \u003c\/span\u003e\u003cem\u003e\u003cspan\u003eThe mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance.\u003c\/span\u003e\u003c\/em\u003e\u003cspan\u003e Cell Metabolism, 21(3), 443–454.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"isSelectedEnd\"\u003e\u003cspan\u003eLu, H., Tang, H., He, J., et al. (2019). \u003c\/span\u003e\u003cem\u003e\u003cspan\u003eMOTS-c peptide regulates adipose homeostasis to prevent metabolic dysfunction.\u003c\/span\u003e\u003c\/em\u003e\u003cspan\u003e Nature Communications, 10, 468.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eShen, W., \u0026amp; He, J. (2020). \u003c\/span\u003e\u003cem\u003e\u003cspan\u003eMOTS-c: A novel mitochondrial signaling peptide with implications for aging and metabolic regulation.\u003c\/span\u003e\u003c\/em\u003e\u003cspan\u003e Frontiers in Endocrinology, 11, 605.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eResearch compound only. Not for human consumption\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e","brand":"My Store","offers":[{"title":"Default Title","offer_id":54735573057865,"sku":null,"price":28.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1019\/7493\/3833\/files\/MOTsC10mg.png?v=1782667350","url":"https:\/\/truformlabs.co.uk\/products\/motsc-10mg","provider":"TruForm Labs","version":"1.0","type":"link"}