{"product_id":"ghk-cu","title":"GHK-CU","description":"\u003ch3\u003eWith \u003cstrong\u003e\u003cem\u003eFREE\u003c\/em\u003e\u003c\/strong\u003e BAC Water\u003c\/h3\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eCOA available upon request\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003e\u003cspan\u003eMOTS-c Peptide\u003c\/span\u003e\u003c\/h2\u003e\n\u003ch3\u003e\u003cspan\u003eOverview\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp class=\"isSelectedEnd\"\u003e\u003cspan\u003eMOTS-c is a naturally occurring peptide encoded by mitochondrial DNA, distinguishing it from most peptides investigated in biomedical research. It has attracted considerable attention in preclinical studies because of its potential involvement in metabolic regulation, energy balance, and cellular adaptation to stress. Although it is not approved for clinical or therapeutic use, MOTS-c continues to be widely explored in laboratory and academic settings, particularly in research related to metabolism, aging, and physical performance.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eResearch Applications\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp class=\"isSelectedEnd\"\u003e\u003cspan\u003eCurrent preclinical research has identified several areas where MOTS-c may play an important role:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"isSelectedEnd\"\u003e\u003cstrong\u003e\u003cspan\u003eMetabolic Function\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan\u003eExperimental studies have examined MOTS-c for its potential influence on glucose utilization, lipid metabolism, and overall metabolic balance.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"isSelectedEnd\"\u003e\u003cstrong\u003e\u003cspan\u003eExercise Science\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan\u003eResearch suggests that MOTS-c may reproduce or enhance certain physiological adaptations associated with exercise, making it an area of interest for studies involving endurance, muscle function, and athletic performance.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"isSelectedEnd\"\u003e\u003cstrong\u003e\u003cspan\u003eHealthy Aging\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan\u003eScientists are investigating the peptide's potential involvement in cellular maintenance mechanisms and biological pathways associated with longevity and age-related health.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"isSelectedEnd\"\u003e\u003cstrong\u003e\u003cspan\u003eCellular Stress Adaptation\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan\u003eMOTS-c has also been studied for its possible ability to support cellular resilience by helping cells respond to oxidative stress and metabolic challenges.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"isSelectedEnd\"\u003e\u003cspan\u003eCollectively, these findings position MOTS-c as a promising subject within mitochondrial peptide research, with particular relevance to metabolism, energy regulation, and the biology of aging. Further research is required to better understand its mechanisms and potential applications.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eTechnical Specifications\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul data-spread=\"false\"\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan\u003eChemical Name:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Mitochondrial-Derived Peptide MOTS-c\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan\u003eAlternative Names:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e MOTSc; Mitochondrial Open Reading Frame of the 12S rRNA Type-c\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan\u003eMolecular Formula:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e C₃₇₇H₆₄₀N₁₀₆O₁₂₆S\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan\u003eMolecular Weight:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Approximately 2171 g\/mol\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan\u003eAmino Acid Sequence:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan\u003eCAS Number:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e 1465911-04-7\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan\u003ePeptide Class:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Mitochondrial-Derived Peptide (MDP)\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cspan\u003eStorage Recommendations\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul data-spread=\"false\"\u003e\n\u003cli\u003e\u003cspan\u003eThe lyophilized peptide remains stable at room temperature for short durations.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eFor extended storage, maintain at temperatures of \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003e−20 °C or lower\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eAfter reconstitution, store refrigerated between \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003e2 °C and 8 °C\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e. Stability following reconstitution will depend on the solvent and storage conditions.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cspan\u003eSolubility\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp class=\"isSelectedEnd\"\u003e\u003cspan\u003eDepending on its formulation and purity, MOTS-c can be dissolved in sterile water or appropriate aqueous buffer solutions.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eReferences\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp class=\"isSelectedEnd\"\u003e\u003cspan\u003eLee, C., Zeng, J., Drew, B. G., et al. (2015). \u003c\/span\u003e\u003cem\u003e\u003cspan\u003eThe mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance.\u003c\/span\u003e\u003c\/em\u003e\u003cspan\u003e Cell Metabolism, 21(3), 443–454.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"isSelectedEnd\"\u003e\u003cspan\u003eLu, H., Tang, H., He, J., et al. (2019). \u003c\/span\u003e\u003cem\u003e\u003cspan\u003eMOTS-c peptide regulates adipose homeostasis to prevent metabolic dysfunction.\u003c\/span\u003e\u003c\/em\u003e\u003cspan\u003e Nature Communications, 10, 468.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eShen, W., \u0026amp; He, J. (2020). \u003c\/span\u003e\u003cem\u003e\u003cspan\u003eMOTS-c: A novel mitochondrial signaling peptide with implications for aging and metabolic regulation.\u003c\/span\u003e\u003c\/em\u003e\u003cspan\u003e Frontiers in Endocrinology, 11, 605.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cem\u003e\u003cstrong\u003eResearch compound only. Not for human consumption\u003c\/strong\u003e\u003c\/em\u003e\u003c\/span\u003e\u003c\/p\u003e","brand":"My Store","offers":[{"title":"50mg","offer_id":54730058858825,"sku":null,"price":19.5,"currency_code":"GBP","in_stock":true},{"title":"100mg","offer_id":54730058891593,"sku":null,"price":32.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1019\/7493\/3833\/files\/GHK-CU_50mg_22fc29ce-6cc0-40c5-837d-a07fc614d388.png?v=1782648150","url":"https:\/\/truformlabs.co.uk\/products\/ghk-cu","provider":"TruForm Labs","version":"1.0","type":"link"}