{"product_id":"cargrilintide-5mg","title":"Cargrilintide 5mg","description":"\u003ch3\u003eWith \u003cstrong\u003e\u003cem\u003eFREE\u003c\/em\u003e\u003c\/strong\u003e BAC Water\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eCOAs available upon request\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003e\u003cspan\u003eCagrilintide\u003c\/span\u003e\u003c\/h2\u003e\n\u003ch3\u003e\u003cspan\u003eOverview\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp class=\"isSelectedEnd\"\u003e\u003cspan\u003eCagrilintide is a long-acting synthetic analogue of amylin, a peptide hormone naturally co-secreted with insulin by pancreatic β-cells. Structural modifications have been incorporated to extend its biological activity, making it a valuable research compound for investigating appetite regulation, energy homeostasis, and metabolic signalling.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"isSelectedEnd\"\u003e\u003cspan\u003eDeveloped to study the physiological effects of sustained amylin receptor activation, Cagrilintide has become an important peptide in laboratory research exploring nutrient intake, gastrointestinal physiology, and endocrine function. Supplied exclusively for research applications, it continues to be investigated in experimental models of metabolic regulation and energy balance.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eResearch Applications\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp class=\"isSelectedEnd\"\u003e\u003cspan\u003ePreclinical and experimental studies have investigated Cagrilintide across several areas of scientific interest:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"isSelectedEnd\"\u003e\u003cstrong\u003e\u003cspan\u003eAmylin Receptor Activation\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan\u003eResearchers study Cagrilintide for its ability to activate amylin receptors, providing a useful model for understanding the role of amylin signalling in appetite regulation and metabolic physiology.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"isSelectedEnd\"\u003e\u003cstrong\u003e\u003cspan\u003eEnergy Homeostasis\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan\u003eExperimental models have explored the peptide's influence on food intake, satiety signalling, and overall energy balance, making it an important research tool in metabolic biology.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"isSelectedEnd\"\u003e\u003cstrong\u003e\u003cspan\u003eGastrointestinal Physiology\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan\u003eLaboratory investigations continue to examine Cagrilintide's effects on gastric emptying and digestive hormone interactions, contributing to a greater understanding of gastrointestinal regulation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"isSelectedEnd\"\u003e\u003cstrong\u003e\u003cspan\u003eCombination Incretin Research\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan\u003eCagrilintide is frequently studied alongside GLP-1 receptor agonists to investigate potential interactions between amylin and incretin pathways, allowing researchers to examine complementary mechanisms involved in metabolic and endocrine signalling.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"isSelectedEnd\"\u003e\u003cspan\u003eThese characteristics have established Cagrilintide as a valuable research compound for laboratories investigating amylin biology, appetite regulation, endocrine physiology, and metabolic function.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eTechnical Specifications\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul data-spread=\"false\"\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan\u003eChemical Name:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Cagrilintide\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan\u003eAlternative Names:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e AM833\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan\u003eMolecular Formula:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e C₁₉₄H₃₁₂N₅₄O₅₉S₂\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan\u003eMolecular Weight:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Approximately 4,187 g\/mol\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan\u003ePeptide Structure:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Long-acting synthetic amylin analogue with lipid modification for extended activity\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan\u003eCAS Number:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e 1415456-99-3\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan\u003ePeptide Classification:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Synthetic amylin receptor agonist\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cspan\u003eStorage Recommendations\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul data-spread=\"false\"\u003e\n\u003cli\u003e\u003cspan\u003eLyophilized Cagrilintide remains stable at room temperature during short-term handling.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eFor long-term storage, keep the peptide at \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003e−20 °C or below\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eFollowing reconstitution, refrigerate between \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003e2 °C and 8 °C\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e. Stability after reconstitution will depend on the solvent used and storage conditions.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cspan\u003eSolubility\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp class=\"isSelectedEnd\"\u003e\u003cspan\u003eCagrilintide is generally soluble in sterile water, bacteriostatic water, and compatible aqueous buffer solutions, depending on formulation and purity.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eReferences\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp class=\"isSelectedEnd\"\u003e\u003cspan\u003eLau, J., Bloch, P., Schäffer, L., et al. (2015). \u003c\/span\u003e\u003cem\u003e\u003cspan\u003eDiscovery of the once-weekly glucagon-like peptide-1 (GLP-1) analogue semaglutide and related long-acting peptide technologies.\u003c\/span\u003e\u003c\/em\u003e\u003cspan\u003e Journal of Medicinal Chemistry, 58(18), 7370–7380.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"isSelectedEnd\"\u003e\u003cspan\u003eFrias, J. P., Bastyr, E. J., Vignati, L., et al. (2021). \u003c\/span\u003e\u003cem\u003e\u003cspan\u003eThe efficacy and safety of the amylin analogue cagrilintide in people with overweight or obesity.\u003c\/span\u003e\u003c\/em\u003e\u003cspan\u003e The Lancet, 398(10317), 2160–2172.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eKapitza, C., Dahl, K., Jacobsen, J. B., et al. (2021). \u003c\/span\u003e\u003cem\u003e\u003cspan\u003eEffects of the long-acting amylin analogue cagrilintide on appetite regulation, gastric emptying, and energy intake in clinical research.\u003c\/span\u003e\u003c\/em\u003e\u003cspan\u003e Diabetes, Obesity and Metabolism.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cem\u003e\u003cstrong\u003eResearch compound only. Not for human consumption\u003c\/strong\u003e\u003c\/em\u003e\u003c\/span\u003e\u003c\/p\u003e","brand":"My Store","offers":[{"title":"Default Title","offer_id":54730048930121,"sku":null,"price":40.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1019\/7493\/3833\/files\/Cargrilintide_5mg.png?v=1782666790","url":"https:\/\/truformlabs.co.uk\/products\/cargrilintide-5mg","provider":"TruForm Labs","version":"1.0","type":"link"}